La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Jack Howard - Forced update

    I had not updated Quicken in several years and was surprised in the changes. I tried to use another free financial software that high recommendations but it was a big disappointment. All I use the program for so to balance my checking and savings accounts so don't need all the extras. That is why I had not updated, but after having to change to Windows 8 I was forced to. I have used Quicken for many years and it seems to be a very good program.

  • Carolyn - Ultra Clean

    I'am a previous user of the Zydot product and if use correctly it does work, and the longer your hair the more packs you will need; I have about 4-5 inches of hair so the one pack did work, I do recommend this product. But wish it offered more in the packaging.