La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Home - Acromegaly is a hormonal disorder that most commonly occurs in middle-aged men and women. The prevalence of acromegaly is approximately 60 cases per million population, and the incidence is 3.3 new cases per million per year. The name "acromegaly" comes from the Greek words for "extremities" (acro) and "great" (megaly), because one of the most common symptoms of this condition is abnormal growth of the hands and feet.

Country: 104.25.225.35, North America, US

City: -122.3933 California, United States

  • john hastings - not what I expected

    Came from the Outlook Express environment and was told to use this over the 2013 version, but have found it very quirky. Constantly disconnects from IMAP servers and hangs up on emails going out. Usually have to close and reopen, then re-send the email again. Very time consuming. I dislike Outlook, but not sure what other option I have for working. You might as well jump to the newest 2013 and skip the old stuff.

  • Miild Mannered Mick - This is just as good as the earlier ones

    Dilbert is something I don't get tired of. This is just as good as the earlier ones, it makes me laugh. Glad I am retired and away from it.... the disfunction that is.