La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • William J. Shryer - Hype

    This is truly amazing that such an old ingredient can still be marketed as something new. Folks, this is plain old benadryl used in just about every night time cold OTC imaginable. It's also the most common nasal decongestant in all of the OTC medications. If you want to save money ask your pharmacist for what is the cheapest diphenhydramine they sell.

  • amitch - Something is very wrong with this printer

    I had so many issues trying to get this thing to work it was ridiculous. I would install it, computer would recognize it, plug into POS hardware setup, print out trial receipt no problem. First few transactions I'd run through it, prints out receipt no problem. Then it starts to only print 3/4 of the receipt, then 1/2 of the receipt, then 1/4 of the receipt, then nothing at all. Uninstall and reinstall same issue. I went through this about 5 times before calling a tech guy out. My tech guy spent 2 HOURS trying to make it work. He kept running into the same problem as me. Eventually he just gave me one of his printers because clearly this thing is possessed. It also started smoking a few times. I believe one of the other reviews mentioned that theirs caught on fire? I didn't have it go that far, but what would happen is it the thermal printer would be printing, but the feed would not be feeding the paper so it would burn clean through the paper and start smoking. Definitely would recommend ponying up the extra $50 to get a decent receipt printer!

  • jesse daniel beisner - Love them!

    Amazing product I recommend if you do have these get them! I wanted something to cover my entire back carpet and this did the job