La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Mami T - Happy with my purchase!

    Small and hardly noticeable. Signal is decent and battery life is okay. Works great for discreetly listening to music and still being able to carry on a conversation. Easy to pause music or end call just by the touch of one button.

  • N. Wilkinson - This is a great bra

    I love this bra! I first found it in JC Penny's but only bought two, and when I went back to buy a couple more I couldn't find any in my size and color so I went online. It sure was good to find them on Amazon. Now I have to admit part of its appeal is that it fits me, and since I'm rather small that is sometimes tough, especially when I don't want to be squished smaller. This bra has a bit of padding to make me look good, but not enough to get scrunched up after being washed. It also doesn't have enough to qualify as one of those "be a size larger!" bras, which I personally find a little embarrasing. The lace provides a feminine look (so its not the bra equivalent of granny panties), but its not sheer and not especially sexy...just a comfortable, everyday bra. I can highly recomment it for anyone small or average size, however if you're large and past the perky stage it my not provide a lot of support - there are no underwires (which I'm always afraid will set off airport security alarms; although they haven't yet).