La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Catskill Water - Don't even try!

    Magic Jack is nightmare. When I got the devise, I tried it as they say on their website. It is supposed be very easy & simple. It didn't work, so I contacted MJ online chat. They told me I need to set up an account then it said I have to pay $21 for port my number to them. I thought I didn't know that, but still good deal. So I paid. I was waiting for porting. It took 5 days and I got e mail from MJ. I started to use and found out that I have to dial area code all loco calls, I couldn't get any incoming call, nor calling to next town. Obviously it's not working. I contact online chat, it's useless. I use phone as business, this is big problem. I canceled MJ. Now the number has to go back to Time Warner. MJ held my number 2 weeks. I've been calling TW & chatting MJ every day in first week. MJ said my number was ported out which was lie. Now 2 weeks later, MJ trying to charge me $32 for port out (I already paid $21 for porting) and none of those charge wasn't mentioned when I bought devise. TW trying to get back my number . I'm hoping it works, but worst case, I have to pay MJ again otherwise I loos my phone number. I don't believe any of good review of MJ. DO NOT EVEN TRY!

  • Sandy L. McMahon - Life Saver for Storage Closets!

    We just recently moved from a very dry climate to a very humid one. These have been life savers for our house (for 2 storage closets in particular). I can literally feel the difference in the air in the room and I love that it protects my belongings in storage from moisture. Will for sure be purchasing on a regular basis!

  • Jana Snodgrass - Living Cookbook 2013

    I love this program. I love the ease of adding recipes. Wish I had bought it earlier. Would definitely recommend it!