La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Chris Dendrinos - Mopar for less

    These bezels are the same as the ones shown to me at the dealership, just for a lot less $$! Super easy to install (just had to pop the old ones out with a puddy knife and painters tape to protect the cars paint) they look much better than the flat black ones. Buy them.. Now!

  • Jason A Edwards - Save Money with time warner cable!

    I have Time warner cable in NE Ohio and I have been renting a cable box for yeas. After giving them thousands of dollars I finally wised up and purchased this $53 unit and that bill will never see me again. It will pay for itself in 6 short months. What a nice lifeHack!

  • Craig Alvaro - Fun (but pricey in the long run)!

    Super, active, family fun! While edited, some spngs may be a bit racy for younger ears, but it's ultimately nothing they couldn't catch on the radio. The subscription service is really mecessary to get the most out of this game, though, which is a bit of a bummer. Other than that, the looks great, sounds great, and PLAYS great!