La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • ElectroniCali - Best diaper cream by far

    I LOVE this cream. Used it for both of my kids as soon as I saw red in the diaper area and they have never had a diaper rash. My 4 year old obviously isn't in diapers anymore but I used this with him and he never had one diaper rash. Using it for my little girl now and so far, her bum is nice and clear. If they get red, use it and the next day, the irritation is gone. I HIGHLY recommend this cream. So glad I found it. I got a 2 pack. Threw one in the diaper bag and one is at home. It is expensive BUT it lasts a long time because it works. You don't have to use it every day. Only if you see them getting irritated and by the next day, it will be better. Also, it has no odor which is good because I can't stand smelly diaper creams. The only downside is that it is hard to get off in the bath but that's a good thing in a wet diaper so it doesn't bother me.

  • mike keil - Cheap and Small

    The jersey was much too small and made of cheaper materials than I had expected. It's not a good value for the price.

  • Kara Carrero {Extremely Good Parenting} - Second time clek owner - favorite seat around!

    This is my second clek fllo car seat and I LOVE it. The fabric is different from the first drift car seat I purchased which makes them look like they don't match, but I think it's because it's easier to clean now. HIGHLY recommend this seat as it's easy to install and love the high rear-facing limit. I have a 2.5 year old in one and a 4 month old in the other (would have had her in one sooner, but the infant insert to put her shoulders at the correct height wasn't available.) Thanks for an awesome product Clek!