La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    Country: 173.201.173.252, North America, US

    City: -111.8906 Arizona, United States

  • Krista K. Bracy - Nice smell but it fades quickly once the bar is ...

    Nice smell but it fades quickly once the bar is open and in the shower. I can barely smell it anymore.

  • Heather belle - Always a wonderful read

    I look forward to this series every year. These 'stories' are the most poignant of all the volumes I have read to date.

  • Karen Bates - Very informative

    Very clearly written and guarentees that you will pass the boards.... I graduate in May so we shall see ....

  • Reza - Definitely read this.

    This book is very technical and well presented. It helps you learn what and why you hurt before you fix it. The stretches, drills and information in this book are very good. I am a golfer and I recommend this to anyone who might have back pain.