La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Eric Gustafson - OK but expected more

    I pre ordered this for my 9 year old daughter and she absolutely loves it. I would defiantly say it was worth the pre-order price just for the fact that it puts a smile on her face.

  • tyler - Kava is a great way to transition off of bad medications

    I was on a benzo based medication for a while and I did not like the fact that your body builds a tolerance and they basically dope you up even more. This stuff gives a similar feeling. The kavalactones are NOT water soluble, so for the negative reviews......they may or may not read this but try drinking it with milk or coconut milk or any fatty liquid. It will not be absorbed as well without the presence of a lipid during consumption. I personally opened up the capsules and mixed half and half along with chocolate milk. I think the flavor works incredibly well with creamy chocolate. People say its gross and bitter, but I drink black coffee every morning so, I'm one of those weirdos that isn't effected by the taste. Anywho, cheers everyone! I hope it works well for you.