La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    Having grown up in the 60's and 70's, this was my favorite song of the group 'Badfinger'. Like many, I watched the finale of 'Breaking Bad' when this song is played in the background as the series reaches its end. Immediately I went to Amazon to download it. I wasn't the only one apparently. The song got a huge boost in popularity thanks to its use in the show. Great tune!

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    This little machine makes bottled/canned beer taste the way it was originally intended by the brewmaster. That is the best way to describe the difference in taste. My GF and I aren't big beer drinkers and almost never drink canned/bottled beer, but we do enjoy a beer on tap at a bar occasionally. Fizzics brings the bar tap taste and feel of beer anywhere you want since its battery operated, appropriately sized, and light weight. I would definitely recommend this to anyone who drinks beer.