La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

ELE - Aerospace | Gas Turbines | Automotive Turbochargers - ELE applies its expertise and capabilities to markets which require complex and precisely engineered components. Turbine blades and Nozzle guide vanes

  • http://eleat.co.uk/ele-news/viper-grinding-the-future-of-manufacturing/ Viper Grinding: The Future of Manufacturing from ELE - Viper grinding technology enables engineers to create more intelligent designs by delivering a grinding tool that can be used on multiple axes.
  • http://eleat.co.uk/ele-news/creep-feed-grinding-versatile-machining-for-intricate-forms/ Creep Feed Grinding - versatile machining from ELE - ELE delivers high quality creep feed grinding processes that enable the manufacturing of complex machined parts for aerospace and other sectors
  • http://eleat.co.uk/services/ Technology - Deep Hole Drilling |ELE Advanced Technologies - ELE combines advanced technology with a highly skilled workforce to provide a wide range of engineering manufacturing services, like deep hole drilling.
  • http://eleat.co.uk/services/edm-fhd/ EDM | Fast Hole Drilling | ELE Advanced Technologies - ELE offers high speed milling and turning, honing, electrical discharge machining (EDM), 5-axis machining, fast hole drilling (FHD) and inconel machining
  • http://eleat.co.uk/services/viper-5-axis-grinding/ Viper Grinding - 5 axis machining services from ELE - VIPER grinding is a 5 axis high speed grinding machine capable of machining some of the toughest materials, like nickel-based superalloys. 5 axis machining
  • http://eleat.co.uk/services/laser-drilling/ Pulse Laser Drilling - 5 axis YAG | ELE - ELE have 5-axis YAG Lasers capable of drilling in continuous motion with water line control. The pulse laser drilling machines have a capacity of up to 1m3
  • http://eleat.co.uk/services/precision-grinding/ Precision Creep Feed Grinding | ELE Advanced Technologies - ELE offers creep feed grinding processes , ideal for generating complex forms quickly and efficiently, such as the fir tree root on turbine blades.
  • http://eleat.co.uk/services/stem/ STEM (Shaped Tube Electrolytic Machining) | ELE Advanced Technologies - STEM - Shaped Tube Electrolytic Machining is an acid electrolytic drilling technique for making long deep holes in hard, corrosion resistant metals.
  • http://eleat.co.uk/services/capillary-drilling/ Capillary Drilling - Electro Streaming | ELE Advanced technologies - Capillary drilling is an acid electrolytic technique for drilling small cooling holes in hard, corrosion resistant metals. Also referred to as Electro Streaming
  • http://eleat.co.uk/market-presence/ Markets we serve - ELE Advanced Technologies - ELE Advanced Technologies produces performance-critical components for a range of industrial applications - Aerospace, Gas Turbines, Automotive Turbochargers
  • http://eleat.co.uk/market-presence/aerospace/ Aerospace components| ELE Advanced Technologies - Aerospace companies look to ELE for help with improved engine performance and efficiency. Compressor and Turbine Blades, Exhaust Liners, Nozzle Guide Vanes
  • http://eleat.co.uk/market-presence/industrial-gas-turbines/ ELE Industrial Gas Turbines | STEM Drilling | 5 axis - Reliability and performance are of vital importance to the Industrial Gas Turbines sector, where components work in extreme environments. STEM drilling.
  • http://eleat.co.uk/market-presence/automotive-turbochargers-transportation/ Automotive Turbochargers - ELE Advanced Technologies - ELE manufactures components for automotive turbochargers. Our machining processes enables us to meet the demands of OEM’s looking for extra performance.
  • http://eleat.co.uk/market-presence/wider-industrial-applications-2/ Wider Industrial Applications | ELE Advanced Technologies - ELE applies its expertise and capabilities to a wide range of industrial applications, all of which require complex and precisely engineered components.
  • http://eleat.co.uk/ele-products/ ELE products |Aerospace |Industrial Gas Turbines| Automotive - ELE Advanced Technologies produce performance-critical components for applications in Aerospace, Industrial Gas Turbine and Automotive Turbochargers
  • http://eleat.co.uk/why-use-ele/ Why use ELE? - ELE Advanced Technologies - Why use ELE ? Flexible and responsive - Getting the best from Technology - Creative thinking - Quality focused - Efficient - Customer focused
  • http://eleat.co.uk/case-studies/ Case Studies from ELE Advanced Technologies - ELE specialise in flexible, niche processes which allow us to take on engineering challenges that very few others can manage. These are some case studies.
  • http://eleat.co.uk/approvals/ Quality and Credibility | ELE Advanced Technologies - ELE combines advanced technology with a well trained and highly skilled workforce to provide a wide range of quality engineering manufacturing services.
  • http://eleat.co.uk/approvals/accreditations/ International accreditations | ELE Advanced technologies - ELE have many international accreditations: AS 9100 ISO 9001: 2008 (UK) - TS 16949:2009 (Slovakia) - NADCAP approved NDT, EDM, Laser and Capillary Drilling
  • http://eleat.co.uk/approvals/inspection-process/ Inspection Processes | ELE Advanced Technologies - At ELE we’ve invested in technology and training to ensure our components are of the highest quality, and produced in the most efficient manner possible.
  • http://eleat.co.uk/about-us/ ELE Advanced Technologies |Precision engineering - ELE boasts some of the finest engineering machining processes available today, supplying customers across a wide range of industrial sectors. About ELE
  • http://eleat.co.uk/about-us/our-vision/ The ELE Advanced Technologies - story and vision - The ELE story starts in 1955 when Earby Light Engineers developed its reputation as a supplier of compressor blades to Rolls-Royce.
  • http://eleat.co.uk/about-us/sharing-growth/ Sharing in Growth (SIG) - ELE Advanced Technologies - In April 2014, ELE was successfully selected for the Sharing in Growth (SIG) programme for UK Aerospace suppliers to ensure they have a supply chain fitness
  • http://eleat.co.uk/about-us/our-people/ Our people - creative solutions to engineering problems | ELE - ELE's reputation has been built around our people. Our commitment to training and development ensures that we achieve the best across all areas.
  • http://eleat.co.uk/about-us/careers/ Engineering opportunities | ELE Advanced Technologies - As an apprentice at ELE you’ll be able to combine classroom learning with on-the-job experience to lay the groundwork for an exciting future ELE career.
  • http://eleat.co.uk/locations/ ELE factory locations | ELE Advanced Technologies - The ELE factory operations are run from a purpose-built facility in Colne – and since 2007, a wholly-owned subsidiary based in Slovakia.
  • http://eleat.co.uk/locations/uk/ ELE Engineering factory - UK headquarters | ELE Advanced Technologies - The ELE engineering facility is located in Colne, 70 km north of Manchester airport and houses some of the most sophisticated machining technology in the world.
  • http://eleat.co.uk/locations/slovakia/ ELE Slovakia Site - ELE Advanced Technologies - In 2007 ELE established a new factory in Trencin, Slovakia. The 3,000 sqm facility has the flexibility to produce a variety of engineering components.
  • http://eleat.co.uk/category/ele-news/ ELE Advanced Technologies - Aerospace and Industrial Gas Turbines - ELE Advanced Technologies - News on stories related to Aerospace, Automotive Turbochargers and Industrial gas Turbines

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  • Kellie Mathie - HUGE! Must anchor n several places!

    Loved the float but returned it due to handles r not sturdy. Would prob work if kept at end of pier and anchored n several places. Make sure n take out for rough weather!

  • B.E. - Great classic family game

    I get so tired of the kids wanting to constantly play video games. I decided this year for Christmas no electronics! while that was unrealistic, I did buy a few classic family games. This was one of my favorite game nights games to play and the price was great. So we will be playing SORRY and interacting more with each other this coming up year and less with the console and controllers. I am excited to start family game night with my kids and this in my opinion is the perfect game to start with.