La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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Bought this because I needed help losing a few more pounds. With my diet and exercise, it worked. I'm not saying its a miracle drug in anyway but it did help me lose the extra 7 pounds I was trying to lose.
I received this product for free from Philips Norelco as part of a marketing campaign. With that said, I would recommend this product. Based on previous experiences with electric shavers, I honestly wasn't expecting too much of a good thing. I'm used to shaving with razors on a regular basis, 3-4 times per week. I fully expected for the Philips Norelco 2100 to feel like it was pulling my facial hair out versus cutting it. To my surprise, the shave is quite comfortable and I experienced little to no irritation. Point to Philips for that.