La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • SwankB - It made my hair manageable!

    Arrived in time and in great condition. I took it straight out of the box and put it to work! Heats pretty quickly, and works as promised. I tried it on my hair (which was not freshly washed, and straight out of cornrows, and still saw a great difference. My hair is natural and ridiculously thick, so any 2-in-1 shortcut is welcomed! This thing here kills two birds with one (heated) brush! Although it didn't get bone-straight, it certainly made my hair more manageable...which is a plus in & of its own.

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    I don't dislike the product but I'm not really seeing any change in my milk production so I'm a little disappointed to pay $40+ for another vitamin/supplement that doesn't work. Oh well, never know until you try... I was really hoping it'd work so I could continue to breastfeed my baby girl. 😔 #workingmomproblems

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    I used to keep my fanny pack stuffed with the usual survival gear: knives, nunchucks, etc. Now that I have this t-shirt, it's full of women's phone numbers!