La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Amazon Customer - More like bleach in a jar

    Worst product I've ever put on my face. Smells like acid/bleach. It's yellow instead of white. I think they sent me an expired product. I have a 6 month old and I won't put it on. If it burns my face and my eyes just being on my face (I don't rub it in to my eyes) then it's going to burn his. I wouldn't recommend this to anyone.

  • Bryan Matthews - A perfect fit, if a little upside-down

    This fits my 2002 Ford Mustang. The instructions were a little confusing, but with only six pieces, I was able to solve the puzzle myself. However, upon installing this with a receiver, I found that it was upside-down. The spacer goes on the top for my Mustang instead of the bottom. I'd have to break the tabs off and glue them to the bottom, but I was concerned about it fitting right and maintaining structural integrity. I had to disassemble everything and flip the receiver over.

  • Theresa smith - A great story based on a period of history I was ...

    A great story based on a period of history I was unfamiliar with. Great characters I learned to love.

  • pizzafiend - Not ready for prime time

    Nice looking player with good sound, but the gushing reviews surprise me given the reality of using it for a few days.

  • ken satifka - Did not address my concern

    I mainly purchased this book to try to obtain more specific information regarding my particular concern, which I thought would be relatively common and not require speaking to a tax preparer (I've always done my own taxes and used to work for H@R Block). The IRS publications all seemed vague on this subject and did not give a definitive answer. I scoured this Guide and did not find any more clarification than was found in the IRS pubs. Therefore, I pretty much wasted my money.