La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Sasha L. - Very good, not perfect

    Good: built in solar screen, bassinet turns out to be super comfy and allows moving baby with least amount of disturbance, good steering, good wheels front wheels need to be big to get through bumpy terrain), everything can be zipped off and washed, good resale value

  • arthur contreras - Great product

    At age 34 I started noticing my sluggish mornings and lack of sleep once I tried testro-x I feltnew energy and have been getting more sleep. I even think it made my sex drive go up a lil

  • WiseTravels47 - Cozmo - your chance to own the first pass at the future of interactive 'bots

    So far I'm impressed - Cozmo is not just a "toy"...he is a plastic and metal "being" bursting with personality unlike any interactive device that I've ever experienced. The future is promising to say the least. While he's not perfect, Anki appears to be heavily engaged to make sure he continues to develop and lives up to the hype.

  • Anonymous - Love it but what's with the cover art!?

    Love the band and the video is top notch. Not a fan of the artwork though. Doesn't relate to the 3 Kings theme at all!!