La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • John L. Hale - This book knocked the Fantasy Football cobwebs off my hibernating brain!

    I have to admit I own Joe's books and listen to him on Sirius/ XM radio, but I use his ratings as a base for any lineup I create. This book knocked the Fantasy Football cobwebs off my hibernating brain right in Chapter 1! Joe has put some players and their 2016 situation front and center that weren't even on my radar. Thanks for a great book Joe!

  • Krazy Kev - Works as advertised

    I must get one thing straight, I bought CLR 28 oz just to clean the calcium and lime deposits on my Procto-Silex 1 liter electric water kettle.

  • Robert Duncanson - Great Single**

    Everybody knows women judge men from the moment of first glimpse to the parting at the graveside. (Guys are in for it until they are put into it.)

  • mskhanson - My first experience with an electric shaver and it's not like a razor

    Not the closest shave, but ok. My first experience with an electric shaver and it's not like a razor. However, it holds a charge nicely. OK to use on your legs. Don't go out and buy LectricShave. It stinks, and stinks strongly. Yuk!

  • Jimmy L James - Like most Lego games this one is a lot of ...

    Like most Lego games this one is a lot of fun. Drop-in/ Drop-out couch co-op. The kids enjoy this one as well.