La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

BRILINTA® (ticagrelor) tablets | For US Health Care Professionals - Health care professional information on BRILINTA® (ticagrelor) tablets, an antiplatelet therapy for the treatment of acute coronary syndrome (ACS).

  • https://m.brilintatouchpoints.com/plato-study.html PLATO Study | BRILINTA® (ticagrelor) tablets - Find PLATO study information for BRILINTA® (ticagrelor) tablets, an antiplatelet therapy for the treatment of acute coronary syndrome (ACS).
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  • https://m.brilintatouchpoints.com/acs-guidelines.html Acute Coronary Syndrome (ACS) Treatment Guidelines - BRILINTA® (ticagrelor) tablets is included in major US guideline focused update on duration of dualantiplatelet therapy as part of the standard of care for management of acute coronary syndrome (ACS)
  • https://m.brilintatouchpoints.com/dosage-information.html BRILINTA® (ticagrelor) tablets Dosage & Administration - Find dosage and administration information for BRILINTA® (ticagrelor) tablets, including considerations and administration with other drugs.
  • https://m.brilintatouchpoints.com/antiplatelet-therapy-requirements.html Intitiating Antiplatelet Therapy in Patients With ACS - When starting your acute coronary syndrome (ACS) patients on an antiplatelet therapy, knowing about any potential restrictions is essential.
  • https://m.brilintatouchpoints.com/moa.html Mechanism of Action | BRILINTA® (ticagrelor) tablets - Read about the mechanism of action for BRILINTA® (ticagrelor) tablets, an oral antiplatelet therapy for patients with acute coronary syndrome (ACS).
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