La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • rocknrolldawgie - so-so

    It is okay, but doesn't live-up to the hype. Smells too sweet, reminds me of Stetson or something. I know a cologne is a winner when I get multiple compliments regarding it. This has gotten none so far, which is unusual.

  • Our Journey Red,Black,Green and Vegan - Profound......

    A must to keep in the home for a quick references. You must read it cover to cover at least twice, before using it as a reference book. He is double D bad!

  • Edmond - Peculiar but useful packaging

    I was perplexed at first when I opened this very good looking box and found that instead of a single bottle, there are 8 equally handsome small boxes inside. Each small box contains a foil pack and a disposable shower cap. Since the product is supposed to be 12 ounces, I gather that each foil pack contains one and a half ounce of the hair masque. It sounds like very little, but there is a lot in each pack, especially when I have short hair. I have used the first pack 3 times so far and I am only half way through the pack.

  • John Pratt - Did not seem to work for me

    I bought the Goldenseal to work on blood sugar and water retention. I tried it for a week. I saw no benefits from it. It may work for others but it does not seem to help me.