La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Aortic Stenosis & Heart Valve Replacement Info | New Heart Valve - Find information about aortic stenosis and treatment options like aortic valve replacement through open heart surgery and TAVR.

  • https://newheartvalve.com/what-is-aortic-stenosis About Aortic Stenosis | New Heart Valve - Learn about aortic stenosis information and get information on how to get diagnosed. Understand treatment options like BAV and medication.
  • https://newheartvalve.com/severe-aortic-stenosis-treatment-options Severe Aortic Stenosis Treatment Options | New Heart Valve - Severe aortic stenosis treatment options include transcatheter aortic valve replacement (TAVR) and open heart surgery (SAVR).
  • https://newheartvalve.com/about-tavr/is-tavr-right-for-you What is TAVR (or TAVI) | New Heart Valve - TAVR (or TAVI) is a minimally invasive technique for aortic valve replacement. Find out if TAVR is right for you.
  • https://newheartvalve.com/what-is-important-to-know-about-tavr-as-a-caregiver TAVR Caregivers | New Heart Valve - Important information for caregivers about patients with severe aortic stenosis who may be having aortic valve replacement surgery, known as TAVR.
  • https://newheartvalve.com/watch-tavr-patient-video-stories TAVR Videos | New Heart Valve - Watch videos about the TAVR procedure and hear real stories from people who have undergone transcatheter aortic valve replacement (TAVR).
  • https://newheartvalve.com/about-tavr-tavi About The TAVR Procedure | New Heart Valve - Watch how the TAVR procedure for heart valve replacement works: transfemoral, transapical, and transaortic approach.

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