La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Journal of Ovarian Research | Home page - <p><i>Journal of Ovarian Research</i> is the only open-access journal covering all aspects of ovarian research. <i>Journal of Ovarian Research</i> aims to provide a forum for high-quality basic and clinical research on ovarian functions, abnormalities, as well as prevention and treatment of diseases afflicting the organ.</p>

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    I used to love this hair trimmer until it stopped working after a few months. Changed the batteries, no difference. So, I decided to purchase another one. About a month later, guess what? That one stops working too. Completely shuts down. Don't buy it - it'll last for a few weeks, maybe two or three months max. You might as well invest in a more expensive option.