La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Michael - Brookstone sand is amazing

    This sand is amazing. The best part of this kinetic sand is that it really lives up to its promise of not making a mess. This sand sticks to itself and not you. This is a great buy and I am very pleased with it. I recommend this sand to anyone who is in the market for kinetic sand.

  • Lori - Great test taking tips

    I really appreciate this book so far, since it is full of detailed steps on how to approach NCLEX style questions. There are some practice questions (I got Davis's Q&A for more questions) and I will use all of them, and I like how they show how they arrived at the correct answer.

  • Greifboy - Works great as a computer monitor

    I bought the 40" version of this TV to use as a 4k computer monitor. The resolution and color are fantastic, and it can handle 4k @ 60Hz if you have an HDMI 2.0a output on your computer. If you don't you can get a mini-display to HDMI adapter and it works great. Just make sure you get an adapter that has support for HDMI 2.0a.

  • Troy Agler - Disappointed

    Technically nothing wrong with this helmet. For the price, however, I would expect to receive a well made, light, aerodynamic product, made specifically for an advanced rider. First, the helmet itself did not seem well made. It had flashing all over the place, and seemed kind of flimsy overall. It was very light. In terms of fit, it was awful. It looked like a big mushroom on my head and the strapping was cumbersome and uncomfortable. I returned this product and ordered a Rudy Project Windmax for the same price from a different vendor. Absolutely love the fit and the advanced features (strapping, bug webbing, etc.) of the Rudy Project helmet.