La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • LaTonya Shaw - Premium Look And Feel

    Decent tablet for the price. Can handle apps and games without any problem. Couple of issue you might not like, the camera is the worst quality I've ever seen and the volume is lacking. The good thing is most people don't use the camera on a tablet so you might not even notice that. Overall it's well worth the money. Has a premium look and feel.

  • Black Hole Gang - Preferred because of the shorter interval workouts

    My son prefers this to another he has tried because the other workouts ranged up to 50 minutes long. These are 25 minutes long with another couple of minutes to stretch afterwards. The shorter time makes it more manageable in a tight schedule, he is still sweating and pumped up by the end, and we saw visible improvements after a few weeks.

  • Tasha Crandall - Purchased as a reference for work

    Out of the HR related books I have ordered or purchased, this one was one of the best. It was easy to find topics I needed and explained them in terms normal people could understand without having to call a lawyer to explain.