La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • K Owens - Simple game, but true to story line

    This is my first Lego game and I started playing alone one day when I had some free time. Although the controls are simple, I was still hooked and played through the majority of the "Jurassic Park" story line. I didn't realize this came with the storylines of all the Jurassic Park series. And it followed them pretty closely (with a few allowances here and there to make it more game/kid friendly). I also played with my friend's five year old son. He had never played video games before and he loved it. It took him a few minutes to get used to the controls, and he still got frustrated a few times, but it's a great game to introduce children to video gaming.

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    I am one of those SKEPTICAL people that doesn't believe everything she reads regarding a product. I have to say that after just purchasing this cream, I am seeing a difference, SLIGHTLY but nontheless a difference as this product mentions. I would definitely reccommend this product to friends and family.