La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • C. Smith - Must Uninstall/Reinstall on Windows 10

    Just downloaded this on my Windows 10 computer last night and realized that it was necessary to totally uninstall the previous version, then install this one, kind of ridiculous if you ask me, but it works.

  • Judith Moore - Not a good purchase

    Sent it back. I don't know if I just got a bad one but it did not work at all. It had no suction at all, it dispensed water and cleaner but even after the dispenser was emptied unto the floor it would not pick up any dirty water. Now my beautiful tile has this film on it that I then have to use vinegar to remove and just use a mop now. I read the troubleshooting guide called the 1-800 number but nothing worked.

  • Audrey - Preventitive Medicine

    These do not clear up UTIs no matter how many you take; at least not for me. However, taking two in the morning, two in the evening, and two right after sex has prevented me from getting any more UTIs. It's one vitamin I make sure to take every day!