La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    This is by far one of the best masks I have ever tried! My facialist (who is one fo the best in Los Angeles) recommended this to me. You only need to apply a thin layer, it dries quick. I use it after I open my pores after a hot shower. Works great as a spot treatment as well!

  • Rhonda Neely - Turbo Tax

    The product is fine. The cost continues to go up every year for the same product. Harder to find at a reasonable price but they have customers stuck since they use it! Not happy about the cost.

  • Amanda Carthel - BUY KINDLE FIRE HD INSTEAD!

    It is so slow. My toddler just set it aside and got bored with it too quickly. I sent this back and ordered the KINDLE FIRE HD! So much better. For a learning tablet there are a ton of hidden costs. If i could afford to spend a fortune on education my child would be going to private school! We love Leapfrog products but this one was a failure!