La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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Thought it would NEVER happen; a stainless steel cookie pan/sheet. LOVE IT! No need to worry yourself about the toxic non-stick coated pans, nor the aluminum pans that use to be the ONLY option for baking. Great in the dishwasher (comes out just as bright and shiny as it is when it's brand new). Easy clean-up by hand too. Seems to tolerate temperatures of 350 degrees without warping or bending out of shape. Great job Norpro! Great price AMAZON!!
I am by trade a software engineer. I spent over 20 years in the areas of software design and testing. I am intimately familiar with the Office products and was shocked (dismayed) when the 2010 version came out. My review and therefore the one star rating are based on the following general areas:
I bought this from Amazon after watching the infomercial a few times. I wanted to replace the little green Eureka that I got to keep down stairs
I've been using this for about a year and I really do like it. I notice my "mature" skin feels softer and healthier and some fine lines have been reduced. As far as wrinkle fighting products go this is your best bet. There is no magic in a bottle no mater how much you spend,believe me I've tried so many different products.My skin is in better condition than when i started using ROC and that's a win.No need to spend hundreds of dollars for a luxe line when this will do the same,if not better job. I'll stick with ROC unless someone finds a fountain of youth in a bottle.