La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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So happy to see the return of this character and series. Charlaine Harris is the business, so entertaining and fast-paced and human. I have no doubt I'll re-read this many times, as I have so many of her books.
The antenna on my Equinox was too tall to fit through the entrance to my garage. The Stubby Antenna is just what I was looking for. It definitely is just what I needed. Works exactly the same as the original and looks great. It's nice and compact, just what I needed.
Very happy with the service and response! The antenna works great and it just fits under my garage door without hitting it. Since there was a change by GMC in the threads for the antenna mount there can be some confusion as to which of the two thread sizes you need. I bought my 2011 GMC used and it's possible the mount had been replaced at some time. The threads on my 2011 are what is normally considered for those newer than 2012. So the first one didn't screw on properly. I communicated both by phone and email with CravenSpeed so they could properly identify the correct thread size. They were very helpful and pleasant to deal with, and they sent the correct one out to me immediately. They included a return label so it did not cost me anything to send the first one back.