La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
Drug Development and Delivery Experts | Teikoku Pharma - Teikoku Pharma USA is a pharmaceutical company focused on the drug development and delivery of treatments for CNS, Pain Management and Oncology. Read more.
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I really like this product, my teeth felt extremely clean after brushing with it. The only thing I wasn't happy about was the gritty feeling it left in my mouth. It only happened the first time I used it. I have noticed a difference in my teeth since using it for only a week.
I got these stickers to fill up my book I recently bought. These stickers are awesome! My husband and I have enjoyed seeing which players we've received and which ones we need. I love the hologram looking stickers! It's a little hard to peel the sticker from the backing but it made it a little more fun, kind of like a competition between my husband and I to see who would get theirs peeled fast enough haha. I definitely plan on getting more to finish off my collection!