La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • M. Morris - I love to organize

    I love to organize! This works great! We have it on our dresser and at night each child is to have their device plugged up to charge before their bedtime. Seeing their device charging we know they are going to be asleep not staying up to all hours watching movies or playing games. Since we have 4+ items plugged up at once this really helps organize the outlet. Before buying this it was hard to get all the charging things at one outlet. This has really helped. It charges everything overnight just fine. Have not tried charging anything just for an hour or two because we needed it for overnight. Love it.

  • John Shepherd - Squirrels have fear - the squirrelinator is here!!!

    If your squirrels are used to getting food consistently in a particular location on the ground I am 100% sure this thing will great work for you. I don't know if it would work quite as well if there is a lot of widely dispersed squirrel food and they have lots of options for getting food.