La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Home - Vohne Liche Kennels is the industry leader in Bomb/Explosive Detector dogs training civilian and military working dog handlers worldwide in all phases of Explosive/Bomb dog detection and IED techniques. Our drug/narcotics detection courses train police from around the world in latest techniques. We train all branches of military and police departments from around the world in all phases of tracking/trailing writing and developing courses for the U.S. Army and Marine Corps. Our cell phone and Cadaver dog programs are used worldwide by civilian and military police and personal facilities. No matter if you require single or dual purpose Vohne Liche Kennels can provide you state of the art dogs and training in the U.S. and abroad. Vohne Liche Kennels is the industry leader no matter your K-9 needs.

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