La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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I became interested in this book after hearing an interview with Dr. Cherniske. Although some of the book is of a technical nature, the illustrations, personal stories and plain speech make it a rather fast and easy read. Plus, the hope for a healthier lifestyle found here are encouraging to say the least. I love having a choice and certainly plan to put this information to personal use.
This was an interesting and enjoyable political and psychological thriller. The plot is an homage to "The Manchurian Candidate", with China playing the villain instead of Communist Russia. The star of the book is Erica Sparks, a hard-hitting journalist for GNN (the Google News Network) with the #1 rated news show on TV and a penchant for getting herself into dangerous situations. It is presidential election season and she is trying to angle a slot as a debate moderator to help raise her profile even further. She meets Senator Mike Ortiz, one of the Democrat candidates, and his wife Celeste, before a primary debate. Even considering his history of being kidnapped and tortured by Al Qaeda and then miraculously escaping, there is something about Senator Ortiz that seems "off" to Erica. When Senator Ortiz' primary challenger is killed by a bomb outside the site of the debate and in front of Erica, the Ortiz family, other media, and members of the public and no group claims responsibility and the bomber appears to have no motive for his actions, Erica becomes more curious about the Ortiz family and Senator Ortiz' strange affect/demeanor. Her search leads her deeper and deeper into a mystery and places family, friends, and sources at risk, but she feels compelled to keep on digging and learn the truth.
I LOVE THE MAGAZINE I DESPISE THE KINDLE APP. IT HAS NEVER WORKED WELL. NOW I HAVE A KINDLE 7 HD AND A NEW VERSION OF THE APP AND IT STILL BEHAVES BADLY. UNBELIEVABLE.