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La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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This stuff is really good. I must say that I slept on it at first because of the texture and I was using it on wet hair. The best way to use it is on mostly dry hair with a spray bottle just to add a bit of moisture. I used it for a coil out and only let it set for a couple of hours and it came out great. I'm sold 👍
I just had a baby and started using this 6 weeks after I delivered, and it did help tone my abdominal muscles and be able to do sit-ups and my pilates exercises easier. With diet and exercise, slendertone has helped me loose my baby weight, and loving every single time I use it. Even my husband loves it too. Didn't have to buy any new pads, followed the advice of another reviewer, put a drop or two of purel and works like new!
It has been on my rims for nearly six months now with nary a scratch or noticeable imperfection. Holds up well to hot roads and winter salts. I took my time and did one rim a day. It can be a real PITA to do this correctly. I cleaned the rims with several products and multiple types of brushes, finishing with denatured alcohol. I primed with self-etching primer (1 tack, 2 full). One can finished one rim, front and back (you really have to do the back, unless your rim is solid). One tack and 3 full coats, per rim. Finished with a matte top coat, one tack, three full. Let everything cure for a week or so before washing.
This does the job, the pointed tip is perfect for accuracy. Highly recommend and comes with enough to last awhile.