La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
BioCryst: Home - BioCryst Pharmaceuticals designs, optimizes and develops novel small-molecule drugs that block key enzymes to treat rare diseases.
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Works well in a CTS-V1 (04-07) and plug n play to your existing harness. Programmable buttons so you can pick artist, random, playlists, etc from the head unit, not have to use your phone though you can still do that.
My daughter's friends were all a buzz over this movie so I rented it so she could see what the hype was. I had seen it before, but it was fun to watch it with her. Definitely not Oscar material by any means, but somewhat entertaining, from a "yikes, what the heck would you do if something crazy like that happened?!?!"
Makes me smile whenever I see it. Came fully inflated and works like the usual volleyball. Of course, my kids don't "get" it.
The Flex is fairly good - IF you understand its limitations. And it has a lot of them. This is a 1.0 version, the first wrist-based tracker Fitbit has produced. There are good reasons why there are so many negative reviews of the Flex. I strongly suggest that you wait for the technology to be refined by Fitbit (and others) before spending $100 or more on this.