La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

index - Peter R Breggin MD has been active in psychiatric reform for fifty years. He is called the Conscience of Psychiatry and has founded a new reform organization, http://www.EmpathicTherapy.org. Dr. Breggin is no longer involved with the Center for the Study of Psychiatry, informally known as the International Center for the Study of Psychiatry and Psychology, nor does he participate in their conferences

  • http://www.breggin.org/More-Reform.html More Reform - Dr Peter Breggin's psychiatric reform work and successes--The Conscience of Psychiaty-Peter R. Breggin, MD
  • http://www.breggin.org/BregginReformVideos.html Videos of Dr. Breggin Reform Work - Peter R. Breggin MD psychiatric reform videos including: Psychiatry and Children, Electroshock treatment, Risk of Sudden Death on Psychiatric Drugs, Dr. Breggin's Testimony to the House Committee on Veterans Affairs, US Congress, 2010

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