La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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Country: 50.87.150.249, North America, US
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This 2016 version is not nearly as beautiful as the 2015 star. The glass is dull and does not refract the light with the brilliance of the 2015 model. I purchased two, and they are both the same. While pretty, they pale in comparison to last year's star. Kind of disappointed. It is like the glass was cut, but then not polished.
I'm not hearing any improvment to my radio reception after installing the antenna compared to when there was no antenna installed.