La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Charlie - Another great Longmire mystery/novel that leaves you wanting more

    Another great Longmire mystery/novel. Craig Johnson is masterful in weaving informative history and fact into his fiction and richly developing characters to the point that you can visualize and recognize them among "real life" people you know. Like his other novels, you will quickly immerse yourself in it, hate to put it down, can't wait to pick it up, and at the end leaving you wanting more, and more, and more.

  • Fred Butler - Awesome Box - get a Wireless Keyboard - that will save you hours in searching.

    We use this box almost every day. Always something to watch. Really takes playing with it to get use to it. (This is our firs android tv box) so I really did not know what to expect. I chose a Quad Core so that it would help eliminate buffering but I cannot say that part is true. We have a 12 MB AT&T internet connection (when it works) so that may be part of it. We have had it over a month and the only frustrating part was searching for the movies using the remote.... so get a wireless keyboard remote. This will save you hours in searching. I still haven't figured out how to make wish lists but I am learning. Element walked me through setting it up and loading my first set of apps. I like customer service like that. I paid $129 for this box so if you see it for more than that, you are not getting it from Element Technologies. I cannot offer a compairison to other units because I do not own any other Android TV boxes. Though I do have the Amazon Fire Box (very nice), the Google Chromecast (fun to use with phone but that is it for me) & AT&T Uverse which I am hoping to "Un-Plug" from as soon as I can figure out everything.

  • Dee Bell - Organo coffe

    I hate instant coffee, but I like this. Its rich and does not taste blah like other instants. The purported nutritional benefit is a plus too. Its great for traveling and for places where you dont have the convenience of a coffee maker.

  • justjoan - He's back

    Totally wonderful, had me in tears a couple of times....Go Barry, you got this, welcome back, we've missed you!!!

  • Idrees Graham - update works

    Its easy and simple......once I updated the Navi more roads pulled up. And I'm now able to update my address since before the update the Navi didn't recognize the street.