La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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Bought this for the first time for my guy for his birthday and I have purchased many of the finest men's colognes for him in the past - including Versace - BUT - this is the very first time he ever told me He Loved It!!! Great scent for a man whether for casual or dress.
My first one worked awesome until I left it turned on all day & night and burned it up. My second one works good, but sometimes will leak espresso from the attachment. If I loosen it, clean it, then put it back on, it normally works fine.
I was gifted poo-purri for Christmas. I decided to give it a go. I followed the directions and then began to do my business. I must warn you that when using poo-purri splash back from you poo will cause irritation and burning on your heiny-hole. Use caution while using this product.
I purchased one of these and overall, I think it delivers excellent value for the price. I stumbled across it when I was trying to find the Amazon department that sells manservants, but my quarterly bonus from Goldman Sachs was burning a hole in my pocket and I thought, what the heck? It's my mad money anyway!