La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

D2 medical centre, medical centre in Dublin 2, family practice, GP, doctor in Dublin Ireland - D2 medical is a medical centre located on Fitzwilliam street upper Dublin 2. General family practice, baby and travel vaccine and much more. GP available during opening hours in Dublin 2 Ireland. Doctors available in Dublin 2 Ireland.

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    Country: 217.115.113.37, Europe, IE

    City: -6.2439 , Ireland

  • Nicole - A gift

    Got this to give as a gift and my niece loves it. Its almost two months that shes had it and she still plays on it constantly so i think its money well spent. Its not just a game that a child uses once .

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