La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    Country: 54.84.187.21, North America, US

    City: -77.4728 Virginia, United States

  • Debbie - Perfect!

    This was perfect! My husband and I knew nothing about Rome and this totally helped give us well informed basics of what to do and where to go and how to avoid lines plus great lessons learned about all the sights.

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    I took this for 3 months and it worked! I will definitely take it again, because I believe there is no better product out there.

  • Bargus - Bargus

    My 8-year-old grandaughter asked for this for her birthday and I had searched both book clubs I am in, as well as other sites on the internet, and found this was the best price. It is a beautiful book and I know she will love it!!!!

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    I actually love this case. I thought that going from an otter box to this would bother me, but the fact that I can have my credit cards handy, a few dollars in the side pocket and that I can talk THROUGH the closed case make it really great! I highly recommend it!

  • Yoli - Closed Captions would have been nice.

    The DVD was OK. I bought it as a gift for my father, who likes the Cardinals, but doesn't speak English. I wished it had had subs in Spanish, or at least closed captions in English so he had an idea of what was going on without me having to translate the whole thing.

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    Husband was looking for a new shaver and after doing his research decided on this Philips Norelco Electric Shaver. The shaver and base do not take up much room so it fits easy on the bathroom counter. The instructions for use are was to read and follow.