La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Dutch Daily News - Daily Dutch News in English - Dutch Daily News is your source for Dutch news in English. Latest news, business and headlines from the Netherlands.

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  • http://www.dutchdailynews.com/amsterdam-awarded-prize-sustainability-fund/ Amsterdam awarded prize for sustainability fund - Amsterdam has been awarded a prize for its sustainability fund (the Amsterdam Investment Fund). The jury recognised the fund as “an excellent example of innovation which will significantly improve the city’s sustainability efforts”.
  • http://www.dutchdailynews.com/more-space-for-pedestrians-and-cyclists-in-amsterdam/ More space for pedestrians and cyclists in Amsterdam - Over the next few years, Amsterdam will implement new measures to lessen congestion in the city and create more space in the public areas that are under increased pressure.
  • http://www.dutchdailynews.com/dutch-economy-growing-greener/ Dutch economy growing greener - As reported in Statistics Netherlands’ latest publication Green Growth in the Netherlands 2015, the Dutch economy has become ‘greener’ over the past 15 years.
  • http://www.dutchdailynews.com/netherlands-drops-in-global-innovation-index/ Netherlands drops in Global Innovation Index - The Netherlands placed 9th on the 2016 index, down from 4th in 2015, with Switzerland, Sweden and the Britain ranking highest on the list.
  • http://www.dutchdailynews.com/amsterdam-ranked-third-in-the-world-for-attracting-foreign-investment-projects/ Amsterdam ranked third in the world for attracting foreign investment projects - Amsterdam has been ranked third in the IBM Global Location Trends 2015 report, rising one place from last year’s position.
  • http://www.dutchdailynews.com/netherlands-ranks-top-10-global-competitiveness-index/ Netherlands in Top 10 Global Competitiveness Index - The Netherlands has been ranked 8th in the 2014 Global Competitiveness Index published by the World Economic Forum (WEF).
  • http://www.dutchdailynews.com/brabant-remains-the-favorite-base-for-foreign-multinationals/ Brabant remains the favorite base for foreign multinationals - BOM Foreign Investments again broke its own record when it came to job creation in the province of Brabant last year, with 1,661 new jobs created in 2014 thanks to foreign companies either moving to the region or expanding their operations there.
  • http://www.dutchdailynews.com/rotterdam-name-visit-in-2016/ Rotterdam Named One of World’s Top 10 Cities to Visit in 2016 - Rotterdam featured fifth on the list of top cities for 2016, coming in ahead of Mumbai in India and Fremantle in Australia. Kotor in Montenegro took the top spot.
  • http://www.dutchdailynews.com/t-rex-fly-chicago-amsterdam/ A 66-million-year-old T. Rex to fly from Chicago to Amsterdam - A 66 million-year-old Tyrannosaurus rex fossil flew today from Chicago’s O’Hare International Airport to the Netherlands on KLM Royal Dutch Airlines.
  • http://www.dutchdailynews.com/brexit-slowing-economic-growth-netherlands/ Brexit slowing down economic growth in the Netherlands - The Dutch economy is projected to grow by 1.7% this year. Next year, this will be 1.6%, whereas last June, CPB predicted a 2.1% growth for 2017.
  • http://www.dutchdailynews.com/randstad-acquire-monster-worldwide/ Randstad To Acquire Monster Worldwide - Randstad to acquire Monster Worldwide to transform the way people and jobs connect
  • http://www.dutchdailynews.com/dutch-companies-invited-to-miami/ Dutch Companies Invited to Apply for Economic Mission to Miami - Dutch companies that specialize in innovative solutions in life sciences, healthcare, and sustainable urban solutions are invited to join an economic mission to Miami
  • http://www.dutchdailynews.com/foreign-investment-in-the-netherlands-creates-9300-jobs-in-2015/ Foreign Investment in the Netherlands Creates 9,300 Jobs in 2015 - The Netherlands reported a strong year for foreign investment in 2015, driven by North American projects. The Netherlands Foreign Investment Agency (NFIA) and its regional partners in the Invest in Holland network assisted in the attraction of more than 300 foreign investment projects in 2015, representing $2.04 billion in capital investment and the creation of more than 9,300 new jobs.
  • http://www.dutchdailynews.com/europes-highest-swings-amsterdam/ Europe’s Highest Swings Opened in Amsterdam - The Mayor of Amsterdam opened Europe's highest swings on the observation deck of A'DAM Tower, a unique attraction part of A'DAM LOOKOUT.
  • http://www.dutchdailynews.com/ferris-wheel-pier-scheveningen/ Europe’s First Ferris Wheel Over Sea Opened on The Pier in Scheveningen - The Hague gains a tourist attraction: Europe's first Ferris wheel constructed over sea.
  • http://www.dutchdailynews.com/netflix-app-installed-on-1-7-mln-dutch-smartphones/ Netflix installed on 1.7 million Dutch smartphones - Over 1.7 million Dutch consumers have the Netflix app installed on their smartphones

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  • Catrina - Good read

    Even though much of this book has already been revealed in the press and cable tv,this is still worth tour time and money if you are a poliical junkie like me. It is well researched and written with no partisan agenda. Great review by a great journalist. Highly recommended.

  • James O'Brien - Not What I Expected

    Well, I ordered a 10-pack of these just to be sure. After reading the other reviews I knew it was something I needed to try.