La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Marilee Herman - Customer service is also great if you have questions or problems

    Real dose is not a miracle pill that will make you lose weight while you eat donuts and watch Netflix BUT what it will do is magnify your efforts tenfold and give you that extra boost to stay motivated. Following their enclosed diet guide is a critical element to seeing noticeable weight loss. I also feel that RealDose gives me benefits outside of the weight loss spectrum--better mental clarity and mood enhancement--in addition to helping control appetite and influence weight loss. Customer service is also great if you have questions or problems.

  • Robert M. Brennan - Getting worse instead of better as "fixes" are released 2/4/2014

    I have written to Senior Management as well as Support located in the United States. I had serious problems with Quicken in 2000. Scott Cook, Quicken's founder, looked into it and acted. That is no longer true. I wrote to him and never heard back. A support staffer called back after I chased down the VP of Turbo Tax, and he told me that all of my issues were actually "design improvements" When I pointed out that the "design improvement" either did not work, or did not reflect the real world I got no where.