La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Earline Schuppe - Just ok

    So far I find the recipes are not the type my family would enjoy. Pictures are good and recipes easy to understand.

  • jen toci - I tried this product and spent the day in the ...

    I tried this product and spent the day in the ER in incredible pain. I had a severe reaction to it with my eyelids actually hemorrhaging. The whites of my eyes swelled up with blood and mucous and I still have blood in the whites of my eyes two weeks later. The doctors put me on steroid eye drops and said if I hadn't come in to be treated I might have lost my eyesight in a day or two. I had slight puffiness the morning after the first day I used it and thought I didn't get enough sleep. The next time I used it all hell broke loose. Please be very careful about this stuff.