La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
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Tumbler may be ok, but junk lid ruins it by being way too loose. I ended up going to Walmart to look at the Ozark Trail ones to compare them and I'm sad to say that the Walmart brand blows them out of the water (so I bought two of those). The Ozark Trail feels more substantial, the quality control is better, and the warranty is a LIFETIME WARRANTY. That's better than Yeti and RTIC. After seeing that I'm not alone with the lid issues I'm questioning my prior plan to buy an RTIC cooler until they get their act together. This one is going back to fund buying more Ozark Trail tumblers.
All in all, I'd say I'm satisfied with this product. I've always been a person to squeeze acne bumps on my face, so I have a few scars/marks on my face. Since this was advertised as anti-acne and scar removal, I gave it a try. I've found that it has lightened some of the marks on my face since I've been using it twice a day as directed. Having said that, I have not noticed any decrease in acne overall. Of course this is completely subjective, since I can't say for certain if I would have had more or less acne with or without using this cream. So for me the scar removal has been noticeable, but not so much the anti-acne portion. I'm rating this 4 stars because I am happy about the scar removal.
After seeing how oil filters are made, I have decided that there are only two oil filters that I will use on my car, Mobil 1 and K&N (they are both made from the same manufacture). This is what you use if you love your car.