La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Ian C - These liners are so awesome! I havent even used them yet but removing ...

    These liners are so awesome! I havent even used them yet but removing the stock carpets and fitting these I know they will provide many years of service. They fit perfectly and very easily...almost like they were designed specifically for my make and model. I only had to move my front seats forward and back for ease of installation. Expensive but worthwhile investment!

  • Lisa Saffels - So happy that Damian has finally released his first solo album ...

    So happy that Damian has finally released his first solo album and "This Christmas Time" was worth the wait. It's never too early to listen to Christmas music and this cd starts setting the mood. Hoping he tours with this cd. Definitely a fantastic addition to anyones Christmas Collection.