La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Nick J. Hedman - In the words of my 2nd Grader, "Very Funny."

    We had fun reading this book together and taking turns reading from the different characters. We did not have any deep talk about the theme of perspective, but it was good to read together and giggle.

  • Fireside - ... brands and found them expensive and to give some pretty odd dreams and other side effects

    Ive used a lot of nootropics over the last year or so trying out different brands and found them expensive and to give some pretty odd dreams and other side effects. I like this instead as its a more subtle alternative that still has me being alert. I've been taking 2 caps a day spread out one in the morning when i wakeup and 1 after lunch with lots of water. So far so good no problems with the pills coming back up or any stomach issues, recommend anyone to give this a try.

  • Kay’Reesha Grayson - Hate to see them go buuuuut...

    5 stars of course! The fact that you're able to keep your readers attention IN EVERY SERIES is everything! Love how you finished it off and didn't leave us with questions, everything ended like it should have! I'll miss them all but I know we'll hear from them all soon enough. Keep up the good work, B, you've got it honest when it comes to writing!