La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    Country: 206.145.80.81, North America, US

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  • E. Reagan - Very Educational; Our Elementary Age Kids Love Them

    We have subscribed to these books for 2-3 years now. My two elementary kids love to get them every month or so. They are always looking forward to seeing what the new animals for the month are. I'm frequently met with interesting facts about animals and have learned plenty about all of the animals over the past couple of years.

  • K. Gale - A Good Friend for Over 35 Years

    Various editions of this book have been like a good friend to me for over 35 years--there when you need it, surprisingly helpful, practical, and friendly. I have plenty of other grammar, usage, punctuation, and style books that I've accumulated over the years, but this is a favorite. Having this Kindle edition that I will access on my Android phone and laptop will make it even more available whenever needed.

  • Veronica Power - This book was a great source for me to brush up on certain subjects ...

    This book was a great source for me to brush up on certain subjects since I had been out of high school for several years. It truly is a great way to prepare for the TEAS. I felt confident taking the exam and scored well on it. I recommend this study guide.

  • D. Rock - Quickbooks will end up being a Harvard Business School Case Study on Bad Decision-making

    From the "customer sevice" to the constant upsell, from the online "support" with broken links and unworkable answers, to $149/year support charges, INTUIT is the definition of GREED.

  • Richard Snyder - GARBAGE

    It is hard to get working and at first had to launch it to get it to work with FSX but now it won't even do that! Also does not work with all aircraft. Will never waste my money on any Saitek product again!!!!!

  • Nana Kandy - Great book! I really enjoyed it. Of course I read it last instead of first. All Mandy's books are well written and have great st

    I would recommend any of her books! She's a wonderful author. This whole series was very interesting and well written.