La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Turner White Communications medical journals and medical board reviews for residents, hospital physicians, and managed care decision makers. - Addressing current topics in hospital practice strategies; clinical reviews; clinical, outcomes, and policy issues; CME; and access to medical board reviews.

  • http://www.hospitalphysician.com/smp/smp01.php Turner White Communications - Seminars In Medical Practice - Peer-reviewed journal dedicated to helping residents develop the professional competence needed for effective practice in the contemporary health care environment.
  • http://www.hospitalphysician.com/artindex01.htm Turner White Communications - Article Index - Peer-reviewed medical journal dedicated to helping clinicians and health care executives improve health outcomes with case-based reviews offering CME credit.

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  • Judy - Love it!

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    I so love this series and this one was not a disappointment. While some of the outcomes were predictable, I still would reccomend this series to anyone. I love it

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    My granddaughter was just ecstatic at receiving this Barbie. Other reviews that I read said that they were disappointed that Barbie's arms and legs were stationary .....I don't really care. You buy this doll for her fancy dress and hairdo....if you want a Barbie with moveable legs and arms you get another doll.

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