La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Jackpersad | Specialist Diagnostic Radiologists - Jackpersad are a dedicated team of specialist diagnostic radiologists covering greater Durban and Pietermaritzburg in KwaZulu-Natal.

  • http://www.jackpersad.co.za/services Jackpersad | X-ray and specialised imaging services - Jackpersad provide x-ray and specialised imaging services at numerous private hospitals and medical centres across KwaZulu-Natal.
  • http://www.jackpersad.co.za/branches Jackpersad | Location and branch contact details - Jackpersad's state of the art venues have been set-up and equipped to comprehensively cover all aspects relating to radiology and nuclear medicine.
  • http://www.jackpersad.co.za/medical-professionals Jackpersad | Dedicated medical professionals - Our team consists of specialist radiologists, supported by dedicated radiographers and ably assisted by nursing staff and management.
  • http://www.jackpersad.co.za/contact Jackpersad | Contact us for further information - At Jackpersad we are committed to providing quality health care to each and every patient. Please contact us for any queries you may have.

    Country: 41.79.212.14, Africa, ZA

    City: 31.0167 KwaZulu-Natal, South Africa

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