La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Amazon Customer - Wonderful

    As usual Mark Edwards does it again! I never see the twist coming but when it does it is always a good one. This book is no exception. Keep up with this fast paced thriller or you just might take a wrong turn and wind up in the basement!!!

  • Amazon Customer - Hate this product and do not recommend.!

    I used this product for my house as per the suggestion given by my friend. But i really hate this product I vacuumed the entire house which took almost a day and applied the spray but after 3-4 hours i can see the bugs roaming under my bed. It's waste of money and waste of time .

  • David Charron - Set up is NOT a breeze!

    Once assembled, the E25 model is solid. But boy oh boy is it time consuming to put together. SOLE advertised set up at 25-35 minutes. Come on! It is easily a 3 hour effort! With practice I suspect I could cut that time in half. If you can negotiate "set up" for a reasonable fee, run with it. Otherwise expect to get your heart rate up for the wrong reason.