La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Marla L. Ernest - Hydroxycut Hardcore Elite

    I wasn't sure about this supplement. I'm always looking for major energy. I'm a cancer survivor, a full time teacher, and a grandma who loves to workout. It's hard to have the energy to be all these things. I'm really impressed with HydroxyCut. It's the best energy supplement I've tried. It doesn't give me the jitters. I do have to be careful about what time I take it. It's a bit hard to sleep if I take it too late in the day, but it's perfect before my morning workout. I'll be purchasing this again.

  • Larry Petersen - It was easy to install on my airplane and is working out ...

    It was easy to install on my airplane and is working out great. My problem was that when all the avionics (radios, GPS, strobe light, rotating beacon, panel lights, landing light, etc.) were turned on during flight it produced an electrical drain on the battery. If I didn't fly couple times a month or let the plane sit a few weeks, I would have a dead battery. I attached the BatteryMinder leads to the battery and zip-tied the ends to an engine support. When I am not flying I open the cowl inspection flap and very easily plug in the unit. The next time that I go flying the unit is very easy to remove and I have a strong battery for starting the engine, plus it has been desulfated. I am very satisfied with the unit and has solved the starting problem -"Is the engine going to start, after I roll the airplane out of the hanger".